Question:
Dear Oscar, It is true that Sporanox has never been used to treat psoriasis before. Please recall that this is a new medication. We simply do not know if it will have an efficacy in this realm, but its probable use lies in the suspicion that psoriasis is the symptomatic response to an internal toxin. Case in point: An individual develops thickness, and yellowing of the toenails at the age of 21yrs. old. But no inflammation or pitting characteristic of nail psoriasis. Told that the treatment for nail fungus is very harsh on the body, the person opts to live with the fungus. Twenty-two years later the same person sees his first psoriatic lesion emerge from the skin in the inner ankle. Life was never the same again. When finally diagnosed as pustular psoriasis palmaris and plantaris, the individual had also developed psoriatic arthritis. Looking at the scenario leads one to strongly suspect the possible culprit of an untreated nail fungus… hence sporanox. ~Ebbie
Response:
An individual develops thickness, and yellowing of the > toenails at the age of 21yrs. old. > ~Ebbie
Dear Ebbie, if that leads to a diagnosis of a toenails fungus disease I absolutely agree with the use of the Itraconazole but using Itraconazole to treat P is another matter. There isn’t any known correlation between Itraconazole and P but I hope it may work for our friend. This is an astounding disease or better P are a number of astounding ( and little known ) diseases. So many things may ( or not ) work. Oscar from Italy
Response:
Stephanie, Many antigens act as a trigger for psoriasis. But yeasts are not thought to be primary for it to form. Although a person with systemic candidiasis (internal yeast infection of the bloodstream and other organs) may have a drastic worsening of their psoriasis, and a person with cutaneous yeast, say, under pendulous breasts or in the soft groin tissues may get new plaques in these and other regions, these are just occasional cases — no consistent relationship. I agree with Oscar……I’d question my dermatologist thoroughly about the reason for the Sporonox. Though it’s generally safe, I’d like to know his/her rationale for using it. Bacterial and fungal infections are well-known activators of or worseners of psoriasis. Print this out and take it to your doc. Ask hem to talk to you a minute about this. Dr. Joe
Response:
Hi, My doctor just recently prescribed Sporanox for my psoriasis. I have had plaque psoriasis for 12 years, and nothing has ever cleared it completely. Has anyone ever heard of using sporanox for psoriasis? TIA Stephanie
Response:
> Hi, > My doctor just recently prescribed Sporanox for my psoriasis. I have had > plaque psoriasis for 12 years, and nothing has ever cleared it completely. > Has anyone ever heard of using sporanox for psoriasis? > TIA > Stephanie
Sporanox is a brand name of a strong systemic antifungal agent used for widespread severe cutaneous and mucocutaneous antifungal therapy like tinea corporis, tinea pedis, onychomicosis, candidiasis. It’s closely related to Ketoconazole and his real name is Itraconazole.It appears to have fewers adverse effects than does Ketoconazole and is now preferred over Ketoconazole for the treatment of disseminated hystoplasmosis, aspergillosis and cryptococcosis in immunocompromised patient ( AIDS ).I never heard about the use of Itraconazole for the P , but Dr. Joe for sure knows better the matter. Maybe your doctor is a follower of the candidiasis / psoriasis link. Frankly I smell a rat. Anyway keep us known about your progress. Good luck. Oscar from Italy